8th April 2025
BNF for Children
This update contains 7 significant changes, 2 dose changes, 2…
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8th April 2025
BNF for Children
This update contains 7 significant changes, 2 dose changes, 2 new monographs, and 1 deleted monograph.
Significant Changes:
- Anaemia, iron deficiency: updated guidance for oral iron.
- Emtricitabine with tenofovir alafenamide: new indication and dose for pre-exposure prophylaxis of HIV-1.
- GLP-1 and dual GIP/GLP-1 receptor agonists: potential risk of pulmonary aspiration during general anaesthesia or deep sedation [MHRA/CHM advice] (advice in dulaglutide, liraglutide, semaglutide; see example in liraglutide).
- Immunisation schedule: updated guidance for immunisation against diphtheria, tetanus, pertussis and poliomyelitis in children aged 3 years and 4 months.
- Oral iron: indications and doses updated for iron-deficiency anaemia (advice in ferrous sulfate, ferrous fumarate, ferrous gluconate, sodium feredetate; see example in ferrous sulfate).
- Sodium valproate: new advice for male patients already taking sodium valproate [MHRA/CHM advice].
- Valproic acid: new advice for male patients already taking valproic acid [MHRA/CHM advice].
Dose Changes:
- Dupilumab [update to dosing].
- Evinacumab [update to dosing].
New Monographs:
- Agamree® [vamorolone].
- Joenja® [leniolisib].
Deleted Monographs: Ferrous sulfate with folic acid.
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8th April 2025
British National Formulary
This update contains 11 significant changes, 2 dose changes, 3…
8th April 2025
British National Formulary
This update contains 11 significant changes, 2 dose changes, 3 new monographs, and 8 new preparations.
Significant Changes:
- Apixaban: update to structure of dosing for prophylaxis of stroke and systemic embolism in non-valvular atrial fibrillation and at least one risk factor.
- Bempedoic acid: new indication and dose for established or at high-risk of atherosclerotic cardiovascular disease.
- Cardiovascular disease risk assessment and prevention: updated guidance.
- Dupilumab: new indication and dose for chronic obstructive pulmonary disease.
- Emtricitabine with tenofovir alafenamide: new indication and dose for pre-exposure prophylaxis of HIV-1.
- Fezolinetant: risk of drug-induced liver injury and new recommendations on monitoring of liver function before and during treatment [MHRA/CHM advice].
- GLP-1 and dual GIP/GLP-1 receptor agonists: potential risk of pulmonary aspiration during general anaesthesia or deep sedation [MHRA/CHM advice] (advice in dulaglutide, exenatide, liraglutide, lixisenatide, semaglutide, tirzepatide; see example in liraglutide).
- Immunisation schedule: updated guidance for immunisation against diphtheria, tetanus, pertussis and poliomyelitis in children aged 3 years and 4 months.
- Naltrexone hydrochloride: new indication and dose for gambling-related harm.
- Sodium valproate: new advice for male patients already taking sodium valproate [MHRA/CHM advice].
- Valproic acid: new advice for male patients already taking valproic acid [MHRA/CHM advice].
Dose Changes:
- Ferrous fumarate [update to dosing for iron-deficiency anaemia using oral solution].
- Sodium feredetate [update to dosing for iron-deficiency anaemia using oral solution].
New Monographs:
- Agamree® [vamorolone].
- Joenja® [leniolisib].
- Lunivia® [eszopiclone].
New Preparations: Abilify Maintena® 720 mg or 960 mg prolonged-release suspension for injection [aripiprazole]; Bibecfo® 100/6 [beclometasone with formoterol]; Bibecfo® 200/6 [beclometasone with formoterol]; Luforbec® 200/6 [beclometasone with formoterol]; Proxor® 100/6 [beclometasone with formoterol]; Proxor® 200/6 [beclometasone with formoterol]; Vivaire® 100/6 [beclometasone with formoterol]; Vivaire® 200/6 [beclometasone with formoterol].
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8th April 2025
Critical Illness
This update contains 1 minor updates. Minor updates: Noradrenaline.
8th April 2025
Critical Illness
This update contains 1 minor updates.
Minor updates: Noradrenaline.
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8th April 2025
Palliative Care Formulary
This update contains 1 revised monograph. The following monographs have…
8th April 2025
Palliative Care Formulary
This update contains 1 revised monograph.
The following monographs have been fully revised: Prescribing for children.
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8th April 2025
Stockley’s Interactions Checker
For April, 871 new interactions have been added, and 779…
8th April 2025
Stockley’s Interactions Checker
For April, 871 new interactions have been added, and 779 existing interactions have been updated.
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8th April 2025
Stockley’s Herbal Medicines Interactions
Updates to the nomenclature of several herbs have been made…
8th April 2025
Stockley’s Herbal Medicines Interactions
Updates to the nomenclature of several herbs have been made to align this publication with Martindale: The Complete Drug Reference and Herbal Medicines. Pharmacopoeial information has also been updated.
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