BNF for Children February 2023 Update

This update contains 3 significant changes and 1 dose change.

Significant Changes:

• Dupilumab (Dupixent®): risk of ocular adverse reactions and need for prompt management [MHRA/CHM advice].
• Ibuprofen: updated breast-feeding advice.
• Obesity: updated guidance on management.

Dose Change:

• Crysvita® (burosumab) [update to children’s dosing].