British National Formulary June 2023 Update
This update contains 14 significant changes, 5 dose changes, 1 new monograph, 4 new preparations, 2 deleted monographs and 1 deleted preparation.
Significant Changes:
- Aminoglycosides: pre-treatment screening advice on genetic testing for aminoglycoside exposure posing risk to hearing (advice in relevant monographs; see example in gentamicin).
- Anaemia, iron deficiency: updated guidance for oral iron.
- Camouflagers: title changed to Camouflages.
- COVID-19 vaccines: updated guidance for immunisation.
- Guidance on prescribing: information on national genomic testing directory.
- Metabolic disorders: new guidance on management.
- Oral iron: updated dosing and monitoring advice for iron-deficiency anaemia based on British Society of Gastroenterology guidelines (advice in ferrous sulfate, ferrous sulfate with ascorbic acid, ferrous fumarate, ferrous gluconate, ferric maltol, sodium feredetate; see example in ferrous sulfate).
- Paliperidone: update to once-monthly intramuscular dosing.
- Prescribing in palliative care: updated guidance.
- Respiratory system, drug delivery: title changed to Respiratory system, inhaled drug delivery.
- Respiratory system, inhaled drug delivery: updated guidance.
- “Specialist drug” monographs within BNF Publications: identification and reduced level of detail, see How to use BNF Publications online.
- Terlipressin acetate: new indication for type 1 hepatorenal syndrome.
- Terlipressin acetate: new recommendations to reduce risks of respiratory failure and septic shock in patients with type 1 hepatorenal syndrome [MHRA/CHM advice].
Dose Changes:
- Clarithromycin [update to include dosing for prevention of invasive group A streptococcal infection in children from 6 months old and adults].
- Fentanyl [update to indications and dose for transdermal patches].
- Morphine [update to palliative care indications and dosing for pain, cough, and breathlessness at rest].
- Oxycodone hydrochloride [update to dosing for moderate to severe pain in palliative care].
- Secukinumab [update to dosing for plaque psoriasis].
New Monographs:
- Amvuttra® [vutrisiran].
New Preparations:
- Byannli® [paliperidone].
- Onureg® [azacitidine].
- Testogel® 40.5 mg/2.5 g [testosterone].
- VidPrevtyn Beta® [COVID-19 vaccine].
Deleted Monographs: Atenolol with nifedipine; Tazarotene.
Deleted Preparation: Feospan® [ferrous sulfate].