14th January 2025
Pharmaceutical Excipients
We have released some changes to how Pharmaceutical Excipients content…
Psychotropic Drug Directory supports the optimal and rational use of medicines, to improve the quality of life for people with mental health needs.
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14th January 2025
We have released some changes to how Pharmaceutical Excipients content…
14th January 2025
We have released some changes to how Pharmaceutical Excipients content is displayed on MedicinesComplete to improve your user experience. For more information, see our FAQs here: https://www.pharmaceuticalpress.com/pharmaceutical-excipients-faqs/
This update also contains 1 new monograph (inositol).
14th January 2025
This update contains revisions to Niacin, Pantothenic acid, Riboflavin, and…
14th January 2025
This update contains revisions to Niacin, Pantothenic acid, Riboflavin, and Vitamin B12.
14th January 2025
For January, 1 new medicine has been added, and numerous…
14th January 2025
For January, 1 new medicine has been added, and numerous medicines have been amended.
14th January 2025
This update contains 15 significant changes, 4 dose changes, 4…
14th January 2025
This update contains 15 significant changes, 4 dose changes, 4 new monographs, 3 new preparations and 3 deleted monographs.
Significant Changes:
Cefotaxime: removal of indication and dose for emergency treatment of suspected bacterial meningitis or meningococcal disease, before urgent transfer to hospital, in patients who cannot be given benzylpenicillin.
Ceftriaxone: update to indications and dosing for pre-hospital treatment of suspected bacterial meningitis and meningococcal disease.
Central nervous system infections, antibacterial therapy: updated guidance on management.
Chloramphenicol: updated monitoring advice.
Dexamethasone: update to dose advice for adjunctive treatment of suspected bacterial meningitis.
Diabetic foot infections, antibacterial therapy: updated guidance on fluoroquinolones.
Gastro-intestinal system infections, antibacterial therapy: updated guidance on fluoroquinolones.
Glatiramer acetate: anaphylactic reactions may occur months to years after treatment initiation [MHRA/CHM advice].
GLP-1 receptor agonists: reminder of the potential side effects and to be aware of the potential for misuse [MHRA/CHM advice] (advice in dulaglutide, exenatide, liraglutide, lixisenatide, semaglutide and tirzepatide; see example in liraglutide).
Mavacamten: pre-treatment screening advice on genetic testing for treating symptomatic obstructive hypertrophic cardiomyopathy.
Medical emergencies in the community: update to antibacterials for suspected bacterial meningitis and meningococcal disease.
Medroxyprogesterone acetate: risk of meningioma and measures to minimise this risk [MHRA/CHM advice].
Respiratory system infections, antibacterial therapy: updated guidance on fluoroquinolones.
Urinary-tract infections: updated guidance on fluoroquinolones.
Urinary-tract infections: updated guidance on treatment of lower urinary-tract infections.
Dose Changes:
Cefotaxime [removal of intramuscular route for severe susceptible infections due to sensitive Gram-positive and Gram-negative bacteria, and meningitis].
Ceftriaxone [removal of intramuscular route for meningitis].
Ceftriaxone [update to indications and dosing for meningitis and meningococcal disease].
Fluconazole [update to indications and dosing].
New Monographs:
Iqirvo® [elafibranor].
Piasky® [crovalimab].
Sogroya® [somapacitan].
Voydeya® [danicopan].
New Preparations: Alutard SQ Bee® [bee venom extract]; Alutard SQ Wasp® [wasp venom extract]; Itulazax 12 SQ-Bet® [tree pollen extract].
Deleted Monographs: Belantamab mafodotin; Crizanlizumab; Voxelotor.
14th January 2025
One record has been selectively revised. Pharmacopoeial information has also been updated….
14th January 2025
One record has been selectively revised. Pharmacopoeial information has also been updated.
Selective revision: Ginger.
Minor updates: British Pharmacopoeia, European Pharmacopoeia, and USP-NF information have been globally updated.
14th January 2025
This update contains 13 significant changes, 4 dose changes, 2…
14th January 2025
This update contains 13 significant changes, 4 dose changes, 2 new monographs, 2 new preparations and 2 deleted monographs.
Significant Changes:
Cefotaxime: removal of indication and dose for emergency treatment of suspected bacterial meningitis or meningococcal disease, before urgent transfer to hospital, in patients who cannot be given benzylpenicillin.
Ceftriaxone: update to indications and dosing for pre-hospital treatment of suspected bacterial meningitis and meningococcal disease.
Central nervous system infections, antibacterial therapy: updated guidance on management.
Chloramphenicol: updated monitoring advice.
Dexamethasone: update to dose advice for adjunctive treatment of suspected bacterial meningitis.
Fever: updated guidance on management.
GLP-1 receptor agonists: reminder of the potential side effects and to be aware of the potential for misuse [MHRA/CHM advice] (advice in dulaglutide, liraglutide and semaglutide; see example in liraglutide).
Medical emergencies in the community: update to antibacterials for suspected bacterial meningitis and meningococcal disease.
Medroxyprogesterone acetate: risk of meningioma and measures to minimise this risk [MHRA/CHM advice].
Neonatal infection, antibacterial therapy: updated guidance on management.
Respiratory system infections, antibacterial therapy: updated guidance on fluoroquinolones.
Urinary-tract infections: updated guidance on fluoroquinolones.
Urinary-tract infections: updated guidance on treatment of lower urinary-tract infections.
Dose Changes:
Cefotaxime [removal of intramuscular route for severe susceptible infections due to sensitive Gram-positive and Gram-negative bacteria, and meningitis].
Ceftriaxone [removal of intramuscular route for meningitis].
Ceftriaxone [update to indications and dosing for meningitis and meningococcal disease].
Fluconazole [update to indications and dosing].
New Monographs:
Piasky® [crovalimab].
Sogroya® [somapacitan].
New Preparations: Alutard SQ Bee® [bee venom extract]; Alutard SQ Wasp® [wasp venom extract].
Deleted Monographs: Crizanlizumab; Voxelotor.
New, Psychotropic Drug Directory supports the optimal and rational use of medicines, to improve the quality of life for people with mental health needs.
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Sheila O’Loughlin, Supervising Pharmacist, Killan’s CarePlus Pharmacy, Ireland
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